2: 81
7: 76
1186/s13256-022-03357-z Abstract Background: However, it has been associated with a broad spectrum of side effects
Arrhythmias; cardiovascular disease; diabetes (risk of hyperglycaemia and ketoacidosis, especially with intravenous use);
Therapeutic Indications Dosage Administration Contraindications Precautions and Warnings Pregnancy and Lactation Side Effects Monograph Drugs List salbutamol
During the absorptive phase for 'naive' pigs fed 3 ppm salbutamol
Adverse effects of hypotension Hypotension may lead to poor placental perfusion
hypotension which may lead to foetal distress, cardiac failure, pulmonary oedema and death; hyperglycaemia followed by an increase in serum insulin
23, 24 Fatal outcomes due to anaphylaxis are rare, 25, 26 and around 80% of reactions resolve without (or despite no treatment with) hypersensitivity reactions (angioedema, urticaria, hypotension and collapse) Metabolism and nutrition disorders
ADDITIONAL INFORMATION In acute severe or life threatening asthma ipratropium should be given concurrently with the first dose of salbutamol
Beta blockers are drugs that lower blood pressure and heart rate, but they can also cause life-threatening toxicity in overdose
Bradycardia and hypotension resistant to Salbutamol was administered to pigs previously fed on control diet ('naive'), and in a second study to pigs fed 3 ppm salbutamol for 19 days ('acclimatized')
A head-to-head study comparing the use of salmeterol and salbutamol (albuterol) revealed clinically superior results of inhaled salmeterol, providing sustained bronchodilatation and better prevention of the symptoms of asthma than salbutamol
The overall median time to onset of hypotension was 4 h (interquartile range (IQR): 2-6
The generic name represents the active ingredient in the drug, which is responsible for its therapeutic effects
Salbutamol or albuterol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm
argued that IV administration was associated with increases and decreases in heart rate and diastolic blood pressure [64]
At therapeutic doses, it acts on the beta2-adrenoceptors of bronchial smooth muscle, with little or no action on the ß1-adrenoceptors of cardiac muscle
There have been spontaneously reports of myocardial ischemia in post-marketing experience (frequency unknown, see section 4
Neurologic Salbutamol nebuliser solutions are indicated in adults, adolescents and children aged 4 to 11 years
Salbutamol can be applied via nebulizer or given intravenously
Salbutamol has been shown to be safe and even superior to rectal cation-exchange resin in nonoliguric preterms with hyperkalemia